A year after the death of his friend and partner Sherlock Holmes, Dr. John Watson (Morris Chestnut) resumes his medical career at a clinic dedicated to the treatment of rare diseases. However, Dr. Watson soon finds that his old life is not done with him yet. Watson stars Morris Chestnut, Tommy O’Brien, Eve Harlow, Inga Schlingmann, Bethany Brown, Danny Mac, Shannon Berry, Jean Zarzour, Lesley Mirza, Seham Ahmed, Anita Alfke, Julia Koon, Alessandro Pekin, Lauren Akemi Bradley, Ciara Mandel and Camila Canó-Flaviá.