Grafted centers on Chinese scholarship student Wei, who travels to New Zealand in order to study medical research at a prestigious university. Shy, introverted, and hiding a genetic facial birthmark, Wei is shunned by her social butterfly cousin Angela and her glamorous friends. Determined to change her fate, Wei immerses herself in her late father’s research, working on a revolutionary skin grafting procedure that could cure her deformity. As her experiments take a dark turn, she becomes more dangerous and unhinged, willing to eliminate anyone who threatens her secret.