The drama Painkiller explores the causes and consequences of America’s opioid epidemic, following its perpetrators, victims and an investigator seeking the truth. The series stars Uzo Aduba, Matthew Broderick, West Duchovny, Dina Shihabi, Taylor Kitsch, Sam Anderson, Carolina Bartczak, Jack Mulhern, Ana Cruz Kayne, Brian Markinson, John Rothman, John Ales, Johnny Sneed, Noah Harpster, Darrin Baker, Matt Baram, John Murphy, Cody Porter, Maddy Hillis, Megan Vincent and Laura Afelskie.